New Vaccine Recommendations for the 2025–26 Season
As the crisp autumn air returns, so does the heightened risk of respiratory illnesses across the United States. The Centers for Disease Control and Prevention (CDC) anticipates that this year’s respiratory season will mirror last year’s in terms of hospitalizations from COVID-19, influenza, and respiratory syncytial virus (RSV). With overlapping virus activity expected, staying up to date with vaccinations remains the most effective way to prevent severe illness.
This season’s updated COVID-19 vaccines, developed by Pfizer, Modernay Novavax, have been reformulated to target the latest circulating variants. The CDC recommends that everyone aged six months and older—especially pregnant individuals and those with chronic conditions—consult their healthcare providers about receiving an updated COVID-19 shot. Unlike previous years, this season’s guidance focuses on “shared decision-making.” This means vaccination discussions should be personalized based on individual health risks.
Experts advise getting vaccinated in October or early November, ideally before family gatherings during the holiday season. Vaccination does not guarantee complete protection from infection, but it significantly reduces the severity of illness, hospitalizations, and potential long-term complications.
Flu and RSV Vaccines: What’s New This Year
Influenza continues to be a leading cause of preventable illness each winter, and annual vaccination remains essential. The seasonal flu vaccine is recommended for everyone aged six months and older. Children under nine who are receiving the shot for the first time require two doses spaced four weeks apart. The CDC’s influenza page emphasizes that vaccination should occur before peak flu activity, which typically begins in November. Public health experts recommend getting the flu shot by the end of October to allow time for antibodies to develop.
One major innovation this year is the increased accessibility of at-home vaccination options. The nasal spray version of the flu vaccine, FluMist, can now be self-administered in most states. This makes protection easier for families and individuals who prefer to avoid clinics or pharmacies. Health officials remind the public that it’s safe to receive flu and COVID-19 shots simultaneously if convenient, as no medical contraindication exists for co-administration.
Meanwhile, RSV vaccines are now available for adults 50 and older, as well as pregnant people between 32 and 36 weeks of gestation. This provides protection for both mothers and newborns. Immunizations for infants are also available in the form of antibody injections, offering protection throughout their first RSV season. Experts recommend scheduling these shots in late summer or early fall to ensure optimal immunity before peak virus circulation.
Staying Healthy Beyond Vaccination
Vaccination is a cornerstone of respiratory disease prevention. However, maintaining everyday health habits plays an equally vital role in staying protected. Regular handwashing, adequate sleep, and balanced nutrition help strengthen the immune system. The National Institutes of Health (NIH) notes that practicing respiratory hygiene—such as covering your mouth when coughing or sneezing—can dramatically reduce viral spread in public spaces.
For those at higher risk of severe illness, healthcare professionals also recommend additional vaccines. These include pneumococcal shots to prevent bacterial pneumonia and other respiratory infections. People can further reduce exposure risk by avoiding crowded indoor settings during peak virus season. Also, wearing masks when appropriate, and staying home when feeling unwell are advised.
Doctors emphasize that even mild respiratory infections can disrupt work, family life, and community health when preventive measures are ignored. By combining timely vaccination with good hygiene and self-care, Americans can help curb the spread of COVID-19, flu, and RSV this season. This keeps communities healthier and hospital systems less burdened through the winter months.
